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Second, it reinforces a documentation principle: Z codes should only appear when they add meaningful clinical information beyond what the primary code already communicates

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The parenteral administration also halts the progression of neurological damage associated with B12 deficiency, but the complete improvement of the condition may depend on the severity and extent of the deficiency

Rohit Loomba from University of California, San Diego, most of the subjects under active treatment were classified as MRI-PDFF responders (relative decline in liver fat 30%) compared to placebo after few weeks only

M.et al (2018)