Urva S, Coskun T, Loh MT et al (2022) LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicenter, double-blind, placebo-controlled, randomised, multiple-ascending dose trial
Read the peptide safety guide before considering any unapproved compound
One such substance, LY3437943, has been discovered to exhibit strong agonist activity on three distinct receptors, including the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors
Semaglutide for obesity: Clinical effectiveness and safety
Investigators reference this profile in receptor binding assays, incretin signaling studies, and comparative pharmacology alongside related single and dual agonist compounds
According to the TMates website product pages at time of publication: Semaglutide is listed at $199.00 and Tirzepatide is listed at $297.00