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Prior study has reported that the activation of PPAR/, a nuclear receptor involved in pancreatic islet function and glucose homeostasis, promotes GLP-1 secretion by intestinal L cells

2013;17(6):R283

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The development of procaine in 1904 did not solve the problem of systemic toxicity, and the Committee for the Study of Toxic Effects of Local Anesthetics published a report of 43 fatal cases linked to the use of LAs