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Certainly, untargeted metabolomics would be useful in ruling out IEMs, but whether or not this kind of testing would be most appropriate incorporated into newborn screening programs versus primarily used for confirmation of a clinical diagnosis remains to be seen (169, 170)

Investigated across the following preclinical and in-vitro research areas

To test whether the observed effects were specific to LDHB inhibition and not due to reduced overall LDH activity, we also silenced LDHA expression (Supplementary Fig

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The comprehensive screening and evaluation of carnitine changes in patients with depression is of great significance to studying the development of depression in depth

This is temporary and usually improves once you stabilize your eating pattern