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Genetic mutations Oxidative stress Glutamate (an important neurotransmitter) accumulation and toxicity While causal relationships have not been established, exposure to heavy metals, pesticides, and other environmental toxins has been linked with ALS development

These data were compared with those obtained from healthy control subjects

Red urine Blood in the urine, known as hematuria, is a possible cause of red urine

However, due to the potential for injury to the sciatic nerve, the ventrogluteal muscle is most often used instead