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Side effects happen fast because your nervous system responds right away, even though the drug's long-term weight loss effect develops over time as it accumulates and reshapes your metabolism

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Gallbladder events affected 1-2%, which aligns with rates expected from any rapid weight loss regardless of method

CrossRef Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1YAP Mechanotransduction Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu Advanced Science .2026;[Epub] CrossRef A sex-specific brake on liver oestrogen signalling Pamela Kakimoto, Natalie Krahmer Nature Metabolism .2026

"I have taken for one month which has worked well with my gym routine

One study investigated loss of appetite following laparoscopic sleeve gastrectomy (LSG) through a food cue reactivity task (Li et al., 2019)