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AMPK also serves a role in regulating lipid and protein metabolism by inhibiting the generation of transcription factors that bind to sterol regulatory elements, suppressing the synthesis of lipid biosynthetic enzymes in tissues, inhibiting fat synthesis, increasing fatty acid oxidation and reducing lipid accumulation (173)
doi:10.1038/ejcn.2017.132 Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P
The authors noted that a key limitation of the study is that it was based on US population data and therefore may not be generalizable to countries with lower rates of obesity and metabolic disease
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GLP-1 medicines like Ozempic, Wegovy and Mounjaro are prescription drugs