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While all liver and cancer cells uptake ICG, normal liver cells excrete it at a faster rate, which allows visualization of the malignant cells if the ICG is given well before surgery [42]

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Supported by the Intramural Research Program of the National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892

These clashes involve both side chain and main chain atoms and can therefore not be resolved by altered side chain conformations