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This was a major standout theme at the Becker's conference in Chicago earlier this month
10.1083/jcb.126.2.485 J
Outside the US it is supplied as a research-grade peptide and is not approved for human use by any major regulator
The tumor suppressor BAP1, an H2A deubiquitinating enzyme, can reduce SLC7A11 expression by inhibiting H2A ubiquitination (H2Aub) on the SLC7A11 promoter, thus controlling ferroptosis (Zhang Y.L
These mechanisms suggest that aescin may reduce neurodegenerative processes and maintain brain function
They are listed here as a reference for researchers investigating Dihexa
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