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As a dietary supplement, take one packet | to 2 times per day with or without a meal, or as directed by a healthcare practitioner

Mechanism mapping (Nature Communications, 2025) Identified the disordered p53 transactivation domain as the binding target, adding structural detail to the mechanism

[1] [3] It is metabolised by proteolytic breakdown and beta-oxidation, with the resulting metabolites excreted in urine and faeces

A phase IIb study of the efficacy and safety of tirzepatide in NASH patients is ongoing (SYNERGY-NASH, NCT04166773)

Maintenance sessions and proper sun protection can help slow this process

Wang Y, Zang QS, Liu Z, Wu Q, Maass D, Dulan G, Shaul PW, Melito L, Frantz DE, Kilgore JA, et al