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Acad Res Int

Based upon our rigorous scientific review, in this instance, the strength of evidence of benefits to adult smokers from completely switching to a less harmful product was sufficient to outweigh the risks to youth, said Matthew Farrelly of FDAs Center for Tobacco Products.

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It is proposed that the basis for non-neoplastic lung injuries associated with smoking is disruption of iron homeostasis in cells after exposure to cigarette smoke particle (CSP) (Figure 1)

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They affect younger and healthier people and typically occur in the throat, specifically in the base of the tongue or the tonsil