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The pretreatment of the experimental samples was identical to that of the blank samples

Experimental studies provide direct evidence for their pathogenic role

However, in most cases, a backed-up toilet is caused by items that have been flushed down the toilet that dont belong there

The most uncertain patient was a sporadic female (Patient 23 in Additional Table 1) who presented only a single, small atrophic scar and localized skin hyperextensibility at elbows and knees

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