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This project will test the hypothesis that smoke exposure of lungs with Scnn1b -overexpresssing epithelia is an excellent model of human disease and can be used more effectively than other models to study particular tobacco products or substitutes

1,2 In addition to nicotine, toxic chemicals like cadmium and lead are often found in the soil where tobacco plants grow, and fertilizers often contain nitrates

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This cultural significance explains why modern attempts to recreate Sobranie face such scrutiny