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Increased production of reactive oxygen species (ROS) is a unifying mechanism for several risk factors that induce arteriosclerosis, endothelial cell dysfunction, and cardiac dysfunction (8791)

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This may lead to an increased chance of adverse effects from, or decreased effectiveness of, the other medications

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And without continuing high-pressure campaigns to make cigarette smoking appear socially acceptable and desirable, the place of the habit in American life may steadily decline