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From a health perspective, cigarettes are the ultimate health risk
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Nicotine is an addictive chemical present in tobacco and smoking products such as e-cigarettes and vapes
The following online databases were searched for relevant articles published from inception to 14 December 2018 (for the initial literature search) and from 01 January 2018 to 12 June 2020 (for the updated literature search): Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, MEDLINE, Embase and PsycInfo
Nat Rev Cancer 3 , 733744 (2003)
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