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Methods: Using a pharmacological approach, we modeled the behavioral and neurochemical effects of subchronic (4-day) nicotine (60g/kg, i.v.) or fluoxetine (1mg/kg, i.v.) exposure in adolescent and adult male rats

In Norway and Sweden, the brand became known for its aggressive marketing, where Norwegian and Swedish celebrities stood up and said they "had also gone over to Prince"

Among the young adults in the RAND survey, about half reported using cannabis during the past year, and 43% reported using some type of tobacco or nicotine product during the same period

Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings, 2005

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