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Selection Criteria Studies were included in the review if they met the following criteria: (1) human participants, (2) smoking as the exposure variable and depression and/or anxiety as the outcome variable, or vice versa (depression and/or anxiety as the exposure variable and smoking as the outcome variable), (3) longitudinal study design, and (4) reported primary data not previously reported elsewhere

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Ethics statement The animal study was approved by Institutional Animal Care and Use Committee (IACUC)

Echocardiographic consequences of smoking status in middle-aged subjects

The best way to build an idea of how quickly you get through refills is to give them a try, and keep in mind if you find yourself going through refills too quickly you may need a higher nicotine content refill

King C, Siegel M (2001) The master settlement agreement with the tobacco industry and cigarette advertising in magazines