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In logistic regression analysis, factors related to smoking status such as the number of tobacco products consumed per day, TDS scores, and smoking type were found to be significantly related to alcohol dependence, in addition to the demographic factors of age and sex (the number of tobacco products consumed per day: AOR=1.01

doi:10.1016/j.acvd.2014.10.003

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Toxicology of smokeless tobacco: implications for immune, reproductive, and cardiovascular systems