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The MR p leiotropy residual sum and outlier (MR PRESSO) global test, and multivariable extensions thereof 90 , were used to facilitate identification and removal of outlier instruments to correct potential directional horizontal pleiotropy and resolve detected heterogeneity

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This study showed that nicotine significantly enhanced BOLD activity in these areas during the RVIP task

contributed by Douglas Adam, informal historian It was felt important for morale that cigarettes remained easily available during the 1940-45 Second World War in spite of the rationing and shortages of most commodities