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While vape juice has fewer calories than tobacco cigarettes, some flavours have more calories

The IARC monographs, referencing studies which used various methods of smoke inhalation, concluded that a significantly greater number of pulmonary tumors occurred among mice exposed to smoke than those in the control groups

all studies were included and the ratings are reported in the results

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Of note, healthcare professionals dealing with smokers who frequently relapse, or facing smokers unable or unwilling to quit, may wish to recommend that they try several types of ECs to see if they can find one meeting their needs