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(Though it is notable that some devices, in particular Juul, deliver very high doses of nicotine.) So the FDA is calling for more investigation into whether there is a connection, and asking doctors and the public to come forward if they know about cases

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This paradigm shifted with the advent of high-throughput sequencing technologies, particularly 16S rRNA gene profiling and shotgun metagenomics, which unveiled a complex ecosystem harboring several hundred to over a thousand microbial species across the nasopharynx to alveoli [89]

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Medical devices like nebulizers, however, are not included