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RTs Three Key Takeaways: Increased Respiratory Risk for Early Smokers: Individuals who begin smoking before age 18 have an 80% higher risk of developing respiratory symptoms, such as wheezing and phlegm, by the age of 28 compared to non-smokers

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According to Ken Marians, a DNA replication expert at SKI, an abundance of G-to-T tranversions in DNA is a hallmark of smoking-induced damage and has been dubbed the smoking signature. Different types of environmental factors cause different types of mutations