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Not every brand can claim their pouches contain zero tobacco

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In 2001, a panel of experts wrote a 236-page report for the National Cancer Institute, saying, In fact, the use of these cigarettes may be partly responsible for the increase in lung cancer for long-term smokers who have switched to the low-tar/low-nicotine brands. Another consultant for Philip Morris and the chemical industry, Kenneth Mundt of Ramboll Environ, has attacked the NCI report

Phenotypically, macrophages from cannabis smokers are significantly enlarged and contain large amounts of inclusion bodies and particulates consistent with tar [141]

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Between cigarettes, nicotine levels drop, creating feelings of anxiety and irritability that are then relieved by the next cigarette (1)