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We also demonstrate how to adapt the protocol to expose living ciliated airway epithelial cells to smoke generated by electronic cigarettes (e-cigarettes) on-chip

Supplementary Table 3 contains a complete list of sites detected by CHANGE-seq-BE, Digenome-seq and CHANGE-seq for ABEs targeting B2M , CBLB , CD7 , CIITA , PDCD1 and PCSK9

If quitting smoking is not feasible, consider these alternatives: Fixed dental bridge (if the supporting teeth are healthy) Removable partial or complete dentures Mini-implants, which carry a lower risk Implants with specialized designs for smokers

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Theyre small, discreet, and harder for law enforcement to detect