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Heterogeneity in smokers responses to tobacco control policies

A study published by the National Library of Medicine also found moderate evidence that heated tobacco users have lower exposure to toxicants/carcinogens than cigarette smokers

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A useful preclinical approach for understanding determinants of tobacco abuse involves administration of extracts derived directly from tobacco products that contain nicotine and a wide range of non-nicotine constituents (e.g., Marusich et al., 2019), which may reflect the effects of behaviorally active non-nicotine constituents in the extracts