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Its validity may be due to the inclusion of the time-to-first-cigarette in the morning (TTFC) item, which appears to be especially strongly associated with relapse likelihood 16,17,18 and may be an especially informative measure of heritability of ND 19

Also, you might not get what you ordered if you dont follow the rules

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This approach did not consider hospitalizations where a tobacco-related disease was listed as a secondary diagnosis

Although the genetic association between TUD and ND and BD in general appears not unambiguous (22) there is an obvious interplay between smoking and psychotic BD

Nakamura, S