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Recommendations for ends core measures for TCORS studies

Ponni Subbiah, Pfizer's Vice President of Medical Affairs, told me over the phone, "We feel a causal relationship has not been established, but it cannot be excluded, so it's something we need to evaluate." She also pointed out that nicotine withdrawal is associated with neuropsychiatric events and that "it's important to keep in mind that smoking by itself is associated with an increased risk of suicide--heavy smokers more than light smokers." In the meantime, the company believes the label change it recently made warning people about the possible side effects is sufficient

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This is the eighth in a series of 12 articles The photograph is reproduced with permission from Sutton-Hibbert/Rex