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current nicotine dependence F17.2 Index to Diseases and Injuries References The following annotation back-references for this diagnosis code are found in the injuries and diseases index

Early signs of oral cancer may include persistent sores, lumps in the mouth, white or red patches, and unexplained weight loss

doi: 10.1002/cre2.683

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The escalation can deepen physiological dependence and make discontinuation more challenging, even when withdrawal symptoms are relatively mild compared to other substances