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Your heart rate slows and your blood pressure decreases, which reduces the stress on your heart and blood vessels 12 hours for the level of carbon monoxide in the blood to drop to a normal level so oxygen can more easily reach the heart and muscles A day for nearly all the nicotine to leave your bloodstream A day to start reducing your risk of heart attack or stroke Three days for the bronchial tubes, which carry air from the nose to lungs, to relax so that air can more easily flow in to and out of the lungs Five days for most nicotine by-products to leave the body

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