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This fact known as the gateway effect of e-cigarettes for nicotine dependence and cigarette smoking is of particular importance, as the extensive body of literature provides unequivocal evidence that tobacco use in the form of cigarette smoking is the leading preventable cause of premature death and the major causal factor for ischemic heart disease, stroke, lung cancer, COPD and numerous other tobacco-related diseases that affect almost every organ in the human body (4, 10)

USA 115 , 79017906 (2018)

Other books by Edward Burns

But all their heads were, by this time, in such a confused whirl that they were incapable of grasping anything, and so the man told them to stop where they were, and he would come to them

and smoking rates in Denmark and Iceland show almost no sex difference

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