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What started as a bottom-up community of micro-manufacturers and early adopter vapers (as distinct from smokers) by around 2007 began to attract the interest of Big Tobacco who embarked on a programme of developing their own products and taking over some of the original starts-up

Retailers may receive warnings under the new education initiative

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4 Among SLT users, 75% have leukoplakia, which is sometimes a precursor to oral cancer

These rules apply to all disposable vapes, regardless of whether they contain nicotine or are marketed as nicotine-free

This is the case with chewing tobacco and ischemic heart disease, which our analysis found to have an estimated relative risk of 1.30 (0.295.83) with between-study heterogeneity and 1.30 (0.881.92) without between-study heterogeneity (Table 2