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The hole will get deeper and deeper, (unless and until the addict puts the shovel down and quits digging), but the soul sickness of addiction abhors admitting bottom

Robert Taylor in "A Yank at Oxford" 10

Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, et al

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Smoking is a well-documented risk factor of ischemic stroke and has been shown to have a high prevalence in young ischemic strokes, varying between 40.9% and 55.5% in the largest cohorts, with a trend toward an impact on long-term recurrence, Philip Ferdinand, MBChB, MRCP, a member of the stroke research group at Keele University, and colleagues wrote in Neurology Open Access