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This verse refers to addiction, and it's a well-documented fact that nicotine is an addictive chemical

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Until long-term results are available, it is safer to treat vaping as a habit with risk

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But to control for cross-border trade, the authors of the study could have employed a regional analysis, comparing New England to the Mid-Atlantic, Gulf States, West Coast, etc

The immunosuppressive effects of smoking are thought to account for the increased incidence, disease severity, and mortality attributed to conditions like pneumonia, tuberculosis, meningitis, and hepatitis in smokers (Addissouky et al