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Moreover, shared developmental [8,9,10,11] and genetic [2, 12, 13] vulnerabilities interact with environmental factors [14, 15], collectively increasing risk across drug classes and sustaining persistent polysubstance use and use disorders

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Yet even during these early years, Mulaney has shared that his relationship with alcohol and drugs began at a young age

Cigarette smoke-induced DNA-damage: role of hydroquinone and catechol in the formation of the oxidative DNA-adduct, 8-hydroxydeoxyguanosine