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[117] Religious leaders have often been prominent among those who considered smoking immoral or outright blasphemous
However, over time, it leads to dependency
Smokers of Camels were even encouraged to smoke a cigarette between every course of a Thanksgiving mealas an aid to digestion. Except for a brief period around the Great Depression, per capita cigarette consumption increased steadily until 1953, by which time 47% of American adults were smoking cigarettes and half of all physicians
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Smokers in higher quartiles, which correspond to lower ages at initiation and higher total PY, showed greater risk of MI, stroke, and death, with the highest risk observed in Quartile 4 for MI (HR 2.09 [2.042.14]), stroke (HR 1.55 [1.521.57]), and death (HR 1.57 [1.561.59]) (Fig
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