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[132] [133] Cigarette Trafficking: Introducing the Transnational Dimension of Cigarette Tracking in Europe and Beyond

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Smoking is the major risk factor for COPD, and cigarette smoke (CS)-induced oxidative stress can lead to the damage of airway epithelium and compromise the barrier function, which is the initial step and pathological basis of COPD progression [3,4,5,6]

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When re-interviewed a year later, those who initially reported having used a non-cigarette tobacco product were twice as likely to have smoked cigarettes during the past 30 days and those who used more than one type of product were nearly four times as likely, the study said