does tobacco cause lung cancer Health effects of smoking Smoking is the major cause

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For nearly 200 genetic loci, the researchers identified a variant that affected the risk of tobacco or alcohol use, thereby opening the route for follow-up studies on the functional role of these genetic variants

To be sufficiently powered to detect a similar or smaller effect in the proposed study, we need N = 40 per group to achieve 80% power at two-sided alpha level of 0.05

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