When mass production of pre-rolled cigarettes arrived during the last quarter of the 19th Century, a number of anti-tobacco campaigns discovered that smoking caused stunted growth in children and was harmful to pregnant women
Clin Ther 1988;10(2):183186
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Cigarette smoking remains the leading cause of preventable disease, disability, and death in the United States, accounting for more than 480,000 deaths every year, or about 1 in 5 deaths