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The US FDA has finalized a rule extending its authority to all tobacco products, including e-cigarettes, cigars, hookah tobacco and pipe tobacco, among others, according to an agency press annoucement

A study points out that higher nicotine levels, around 50 mg/ml, are needed to deliver nicotine more effectively and closely match the nicotine delivery of tobacco cigarettes (Farsalinos et al., 2015)

Potentially Bioaccumulative in Certain Cases

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