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First, an initial population was generated, then at each 1-year time step, the survivability of agents was evaluated based on mortality risk factors dependent on their tobacco use history (i.e., Mortality Sub-Model)

J Health Soc Behav 24:385396 Dorey A, Scheerlinck P, Nguyen H, Albertson T (2020) Acute and chronic carbon monoxide toxicity from tobacco smoking

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Not to mention that there are other specific health concerns related to marijuana use

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Swedish Match AB is removing the iconic Red Man name and Native American man image from its 135-year-old brand of chewing tobacco