In the example above, excessive neurotransmission across a Substance P or glutamate synapse in the pain pathway is responsible for the perception of intense pain
To begin answering this question, we will consider two data sources: (1) participant demographics extracted from a systematic review of cannabis pharmacokinetics and/or pharmacodynamics studies and (2) results from the United States National Survey on Drug Use and Health (NSDUH) from years 20022021
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These can include issues around sensitivity, which are caused by damage to the tooth enamel
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