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Over the same period there has also been an increase in proportion of dual users who both vape and smoke non-daily (from 10% to 22%), and who vape daily while smoking less than daily (from 16% to 32%)

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P53 is a tumour suppressor gene that encodes the p53 protein involved in the process of cell apoptosis

doi:10.1016/j.drugpo.2022.103858 35

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Chromatography methods provide adequate sensitivity, but a main challenge includes a significant matrix effect, which results in peak suppression of analytes (Geiss et al., 2016