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The Cavendish methodology used in preparing it makes this leaf worthy of a blending upgrade if you wanted to improve the quality and flavour by adding a touch of top shelf chocolate aromatic such as Moca mixture from the Mission Pipe Shop, San Jose, CA

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Quitting smoking is not easy for most patients, yet today in Australia there are many more ex- smokers than current smokers, indicating that it is certainly possible

Acknowledgments The authors express gratitude to the NGS facility and Mass facility at IISER Bhopal for facilitating the sequencing and mass spectrometry experiments