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While the Food & Drug Administration has not yet begun to enforce the new minimum age, it is expected to begin doing so by the end of 2020

Am J Gastroenterol 114:135142 Sperber AD, Bangdiwala SI, Drossman DA, Ghoshal UC, Simren M, Tack J, Palsson OS (2021) Worldwide prevalence and burden of functional gastrointestinal disorders, results of Rome Foundation Global Study