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It not only affects the smoker but also poses a significant danger to those exposed to secondhand smoke

Food and Drug Administration found that the e-cigarettes studied contained detectable levels of known carcinogens and toxic chemicals to which users could potentially be exposed. Editor's Recommendations

PLoS ONE 8 , e57987 (2013)

Positive Results & the Detection Window (1) Cotinine may stay in the system longer for heavy and regular smokers who have a slower metabolic rate or whose kidney does not clean the nicotine out at a steady rate