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As a result of these efforts and the implementation of measures outlined in the WHO Framework Convention on Tobacco Control (WHO FCTC), it is estimated that the number of tobacco users in the Region has declined from 159 million in the year 2000 to 129 million in 2025an 18.87% reduction

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115: 2621-2627 [DOI] [PubMed] [Google Scholar] 28).Barbieri SS, Zacchi E, Amadio P, Gianellini S, Mussoni L, Weksler BB, Tremoli E: Cytokines present in smokers serum interact with smoke components to enhance endothelial dysfunction