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A previous investigation (Ha et al., 2015) reported that the acute exposure (for 20 min) of mice to CS with added menthol vapor resulted in a 1.5-fold increase in plasma levels of cotinine (a nicotine metabolite) over those observed in mice exposed to CS without added menthol vapor

Evaluation frameworks will need to be easy to understand and implement in order to shift the adoption curve at scale

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Centers for Medicare & Medicaid Services ) The 2025 MIPS performance year spans from January 1-December 31, and data collected for this timeframe must be reported to Centers for Medicare & Medicaid Services (CMS) by March 31, 2026

A third study showed no increase in eCO post-IQOS use sessions 92