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This classification was based on a specific thresholdif the distance is greater than the threshold, the sample falls into a fitted category

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"Self-administration of nicotine during teenage years, when the brain is still developing, may cause some of the developmental processes to proceed inappropriately, in effect sculpting the brains of these adolescents in ways that facilitate the addiction process." Animal self-administration studies have become a standard tool in nicotine research, but investigation into a possible link between adolescent exposure and severity of addiction has been limited and most work has involved male animals, Dr

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