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"Our analyses show that there is significant toxicity in harm reduction products, and reduction of carcinogens in harm reduction mainstream smoke does not necessarily reduce the toxicity of unfiltered sidestream smoke." Researchers developed tests with human embryonic stem cells, which are similar to young embryos, to compare the toxicity of mainstream (inhaled) smoke and sidestream smoke from both conventional and harm reduction cigarette brands

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One particular brand of e-cigarette, called the JUUL, has become very popular with teenagers and young adults

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People in lower-income categories likewise faced a higher risk (12%) of both conditions

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